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Local Antibiotics and the Risk of Antimicrobial Resistance in Extremity Fractures Complicated by Fracture-Related Infection

JBJS -

J Bone Joint Surg Am. 2025 Jun 18;107(Suppl 1):28-35. doi: 10.2106/JBJS.24.01178.

ABSTRACT

BACKGROUND: We evaluated antimicrobial resistance (AMR) patterns following local antibiotic use in a large cohort of patients with fractures from the PREP-IT (A Program of Randomized Trials to Evaluate Preoperative Antiseptic Skin Solutions in Orthopaedic Trauma) study. We hypothesized that, among patients with extremity fractures who developed fracture-related infection (FRI), there would be no difference in AMR rates between those who had or had not received local antibiotic therapy with surgical fixation.

METHODS: This was a secondary analysis of all patients in the PREP-IT trial who developed FRI. Patient demographics, injury and fracture characteristics, and the primary outcome of the presence of an antimicrobial-resistant FRI were evaluated on the basis of whether the patient had or had not received local antibiotics in the operating room prior to, or at, definitive fixation.

RESULTS: A total of 555 FRIs in 546 patients (mean age, 50 years; 39% female; and 82% White) were included. A total of 268 fractures (264 patients) received local antibiotics. The Injury Severity Score and the proportion of open fractures were higher among patients and fractures that received local antibiotics, respectively. There were more Gustilo-Anderson type-IIIB or IIIC fractures in the local antibiotic group, but the rate did not differ significantly from that in the group with no local antibiotics (20% versus 14%; p = 0.14). Other baseline and fracture characteristics were similar between the groups, with the exception of age (lower in the group with local antibiotics). When examining FRIs with gram-positive organisms, we found that 3 (1.7%) of the FRIs in fractures that had been treated with local vancomycin had organisms resistant to vancomycin compared with 2 (0.9%) of the FRIs in fractures for which local vancomycin had not been used (p = 0.67). When examining FRIs with gram-negative organisms, the number of FRIs with aminoglycoside-resistant organisms was 8 (11.6%) among fractures that received local aminoglycosides and 10 (6.2%) among fractures that did not receive local aminoglycosides (p = 0.26).

CONCLUSIONS: Among extremity fractures that developed FRI, we were unable to detect differences in the rates of AMR between fractures treated with or without local antibiotic prophylactic strategies in our analysis of a randomized trial of various skin preparation solutions for extremity trauma surgery. These findings provide cautious reassurance regarding the safety of local antibiotics but underscore the need for further prospective analysis.

LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

PMID:40531179 | DOI:10.2106/JBJS.24.01178

Outcomes Associated with Choice of Prophylactic Antibiotics in Open Fractures

JBJS -

J Bone Joint Surg Am. 2025 Jun 18;107(Suppl 1):19-27. doi: 10.2106/JBJS.24.01123.

ABSTRACT

BACKGROUND: The ideal antibiotic prophylaxis for open fractures is unknown. We evaluated outcomes following different antibiotic prophylaxis regimens for open fractures.

METHODS: This is a secondary analysis of data from PREP-IT. Prophylactic antibiotics were defined as any intravenous antibiotic given on the day of admission. The outcomes were surgical site infection (SSI) within 90 days and reoperation within 1 year. Logistic regression and an instrumental variable analysis that leveraged site-level variation accounted for confounding. Subgroup variation was evaluated by stratifying by Gustilo-Anderson classification (Types I and II versus III).

RESULTS: Of the 3,331 included participants, the mean age was 45 ± 18 years, 63% were male, 73% were White, 21% were Black, 2% were Asian, and 10% were Hispanic. Cefazolin monotherapy (58% of patients), ceftriaxone monotherapy (10%), and cefazolin plus gentamicin (6%) were the most common regimens. In the instrumental variable analysis, the odds of infection did not significantly differ with ceftriaxone use (odds ratio [OR], 1.24; 95% confidence interval [CI], 0.70 to 2.20; p = 0.45) or cefazolin plus gentamicin use (OR, 0.25; 95% CI, 0.03 to 2.04; p = 0.20) compared with cefazolin monotherapy. There were no significant differences between the regimens with respect to infection when stratified by Gustilo-Anderson type. However, we did observe a nearly 3-fold increase in the odds of infection with ceftriaxone use compared with cefazolin monotherapy (OR, 2.73; 95% CI, 0.96 to 7.79; p = 0.06) in Type-I and II fractures, and a 75% decrease in the odds of infection with cefazolin plus gentamicin use (OR, 0.25; 95% CI, 0.03 to 2.02; p = 0.19) compared with cefazolin monotherapy in Type-III fractures.

CONCLUSIONS: Among patients with open fractures, antibiotic prophylaxis with ceftriaxone monotherapy did not provide significant benefits compared with cefazolin monotherapy in preventing infection in Type-I and II fractures. The findings suggest that cefazolin plus gentamicin might reduce the odds of infection in Type-III fractures compared with cefazolin monotherapy, but this difference was not statistically significant.

LEVEL OF EVIDENCE: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.

PMID:40531169 | DOI:10.2106/JBJS.24.01123

Performance of the OTA-OFC3 Classification System for Open Fractures

JBJS -

J Bone Joint Surg Am. 2025 Jun 18;107(Suppl 1):12-18. doi: 10.2106/JBJS.24.01182.

ABSTRACT

BACKGROUND: The purpose of this study was to compare the simplified modification of the Orthopaedic Trauma Association-Open Fracture Classification (OTA-OFC3) with the original OTA-OFC and Gustilo-Anderson classification systems in predicting surgical site infection and unplanned reoperation.

METHODS: This was a retrospective cohort study conducted using the PREP-IT (A Program of Randomized Trials to Evaluate Preoperative Antiseptic Skin Solutions in Orthopaedic Trauma) trial data of patients with open fractures. The OTA-OFC and Gustilo-Anderson classifications for each included fracture were determined by the treating surgeon at the initial irrigation and debridement. The OTA-OFC3 classification was determined on the basis of the highest severity level in any OTA-OFC domain. The study outcomes included surgical site infection and unplanned reoperations within 1 year of injury. Prognostic performance was measured by the area under the receiver operating characteristic curve (AUC), and AUCs were compared between classifications with z-tests.

RESULTS: This cohort study included 3,338 patients with 3,627 open fractures. Surgical site infections occurred for 11% of the open fractures, and unplanned reoperations occurred for 15%. The prognostic performance of the new OTA-OFC3 score (AUC, 0.61; 95% confidence interval [CI], 0.58 to 0.64) did not differ significantly from that of the Gustilo-Anderson classification (AUC, 0.63; p = 0.40) or the 5 OTA-OFC domains (AUC, 0.64; p = 0.32) in predicting surgical site infection. The prognostic performance of the OTA-OFC3 system (AUC, 0.62; 95% CI, 0.59 to 0.64) was similar to that of the Gustilo-Anderson classification (AUC, 0.63; p = 0.34) but was significantly worse than that of the 5 OTA-OFC domains (AUC, 0.69; p < 0.001) in predicting unplanned reoperations.

CONCLUSIONS: Simplifying the OTA-OFC to the new OTA-OFC3 significantly decreased its ability to predict unplanned reoperations and did not improve the ability to predict surgical site infection. These findings indicate that this newly proposed classification system, although clinically simpler, omits important prognostic information captured in the original OTA-OFC. Despite this limitation, the OTA-OFC3 demonstrated prognostic performance similar to that of the commonly used Gustilo-Anderson classification, and it may provide a clinically convenient way to communicate critical OTA-OFC information when all OTA-OFC domains are being assessed for research or quality-improvement purposes.

LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

PMID:40531166 | DOI:10.2106/JBJS.24.01182

Superior capsular reconstruction after failed rotator cuff repair using a fascia lata autograft is associated with inferior outcomes compared to primary superior capsular reconstruction for irreparable massive rotator cuff tears

International Orthopaedics -

Int Orthop. 2025 Jun 18. doi: 10.1007/s00264-025-06568-3. Online ahead of print.

ABSTRACT

PURPOSE: This study aimed to investigate the effect of failed rotator cuff repair (RCR) on surgical outcomes after superior capsular reconstruction (SCR) using a fascia lata autograft.

METHODS: We included 79 patients with irreparable massive rotator cuff tears who underwent SCR using fascia lata autografts between 2018 and 2023, with a minimum follow-up of ≥ one year. Of them, 66 patients underwent primary SCR (primary SCR group) and 13 underwent SCR after structural failure of previous RCR (revision SCR group). Clinical outcomes, including American Shoulder and Elbow Surgeons (ASES) score, Constant score, visual analogue scale (VAS) score, and range of motion, were assessed. Radiological outcomes were evaluated using radiographs and magnetic resonance imaging (MRI) scans. The minimal clinically important difference (MCID) values determined the clinical relevance of the difference in functional outcomes. Graft tears were recorded if graft discontinuity was found on MRI.

RESULTS: The revision SCR group showed worse VAS (2.1 vs. 1.1, P = 0.025), ASES (69.7 vs. 82.4, P = 0.008), Constant (57.1 vs. 64.3, P = 0.016) scores and higher graft tear rates (61.5% vs. 21.2%; P = 0.049) than the primary SCR group. The differences in VAS, ASES, and Constant scores exceeded the MCID threshold in the primary SCR group at a mean final follow-up of 2.1 ± 1.0 years. Conversely, in the revision SCR group, only the difference in Constant score exceeded the MCID threshold at a mean final follow-up of 2.2 ± 1.6 years, and patients with intact grafts showed significantly better VAS score and acromiohumeral distance (both P = 0.030) than those with torn grafts.

CONCLUSION: SCR using fascia lata autograft improved surgical outcomes for primary and revision SCRs. However, revision SCR showed worse outcomes and higher graft tear rates compared to primary SCR.

PMID:40531208 | DOI:10.1007/s00264-025-06568-3

Current perspectives on lacertus syndrome: clinical features, diagnosis, and treatment

International Orthopaedics -

Int Orthop. 2025 Jun 16. doi: 10.1007/s00264-025-06580-7. Online ahead of print.

ABSTRACT

BACKGROUND: Lacertus syndrome (LS) involves median nerve compression by the lacertus fibrosus at the elbow. Often misdiagnosed as carpal tunnel syndrome (CTS), it presents primarily with hand weakness, fatigue, and forearm pain, with less common sensory symptoms.

OBJECTIVES: To review current knowledge on the clinical features, diagnostic methods, and treatment options for LS, highlighting the distinct characteristics that differentiate it from similar conditions.

METHODS: A comprehensive review synthesizing literature on anatomy, pathophysiology, prevalence, diagnostic approaches, and treatment outcomes.

RESULTS: Clinical diagnosis relies heavily on specific provocative tests, including the clinical triad (muscle weakness, localized pain, positive Scratch Collapse Test), Lacertus Antagonist Test (LAT), and visible Lacertus Notch Sign. Diagnostic ultrasound is increasingly preferred for real-time, dynamic assessment. Electrodiagnostic studies have limited diagnostic value due to the dynamic nature of the compression. Conservative treatments include activity modification, nerve gliding exercises, kinesiotaping, and injections (corticosteroids, botulinum toxin). Surgical intervention, typically via minimally invasive or percutaneous release under Wide-Awake Local Anaesthesia No Tourniquet (WALANT), achieves immediate intraoperative strength improvement and high patient satisfaction rates (around 88%).

CONCLUSIONS: Improved clinical recognition of Lacertus syndrome through specific provocative tests and dynamic ultrasound enhances accurate diagnosis. Surgical decompression, especially using the WALANT approach, consistently yields excellent functional outcomes, emphasizing its role as the definitive treatment for resistant or severe cases.

PMID:40522492 | DOI:10.1007/s00264-025-06580-7

Dynamic anterior stabilization for recurrent anterior shoulder instability improves postoperative patient-reported outcomes without restricting shoulder range of motion: a meta-analysis

International Orthopaedics -

Int Orthop. 2025 Jun 16. doi: 10.1007/s00264-025-06581-6. Online ahead of print.

ABSTRACT

PURPOSE: Dynamic anterior stabilization (DAS) is a novel soft-tissue procedure for treating anterior shoulder instability in selected cases. The purpose of the present meta-analysis is to provide the up-to-date evidence on DAS's outcomes, safety and characterize study designs to improve future studies and accelerate technical advancements.

METHODS: A PRISMA guided meta-analysis was performed. Inclusion criteria were human studies, comparative or non-comparative in which DAS was performed as an indication for anterior shoulder instability. Four databases were searched PubMed (via MEDLINE), EMBASE, Web of Science, and Science Direct. ROBINS-I was employed for risk of bias analysis. A random-effects meta-analysis was performed using mean difference (MD) as effect size estimator. Heterogeneity was reported using the I2 statistic. Dichotomous variables were counted and reported as % out of total sample size for each study.

RESULTS: Five studies met the inclusion criteria. A total of 137 patients were available for analysis with a mean age of 27.8 ± 9 years and 108 patients were males. Mean follow-up duration was 37 ± 11 months. Postoperative ASES score showed an improvement of MD = -15.09 (95% CI: -22.35 to -7.38), p < 0.01, compared to the preoperative period. The ROWE score showed a similar improvement, MD = -58.38 (95% CI: -69.88 to -46.89), p < 0.01. Postoperative range of motion (ROM) was not significantly influenced. Active anterior elevation had a MD = -6.07° (95% CI: -15.04 to 2.91), p = 0.19, active external rotation had a MD = 3.7° (95% CI: -7.71 to 15.11), p = 0.53, and active internal rotation, MD = 0.16° (95% CI: -1.4 to 1.73), p = 0.84. Return to play ranged from 80 to 100% while return to competitive sports, reported by a single study, was 33%. The overall complication rate was 8.6%. The overall risk of bias was "serious" or "critical" for all included studies.

CONCLUSION: DAS has been shown to improve postoperative PROMs, does not restrict ROM compared to the preoperative period and has an overall complication rate of 8.6%.

PMID:40522491 | DOI:10.1007/s00264-025-06581-6

The new, minimally invasive anteromedial-distal approach for extraarticular distal-third humeral shaft fractures. Its evolution and first clinical results

Injury -

Injury. 2025 Jun 9;56(8):112515. doi: 10.1016/j.injury.2025.112515. Online ahead of print.

ABSTRACT

Introduction In 2020, we published a new minimally invasive anteromedial distal approach for plate fixation of the humerus (MIAMDAH) to address extra-articular distal shaft fractures in a cadaveric study. After operating on our first patients, it was noted that the distal MIPO window was too small to comfortably fix the plate distally. So, a wider MIPO window was developed to make the surgical procedure more comfortable. This study aimed to evaluate clinical outcomes in patients who underwent surgery using either the original approach or its modified version and to determine whether the modification provided technical or clinical advantages over the original.

MATERIAL AND PATIENTS: Forty-five patients underwent surgery using either the original or modified approach. Twenty-one received the original technique, and twenty-four received the modified one. The primary outcome measured was the Mayo Elbow Performance Scale (MEPS) score at 18 months. The secondary outcome measures included the University of California at Los Angeles (UCLA) score and the elbow motion of the damaged arm at 18 months. A statistical bivariate analysis was performed to compare various subgroups based on the original or modified approach.

RESULTS: All patients were followed for 18 months. The average distance from the fracture to the coronoid fossa was 3.72 cm for the original approach and 3.95 cm for the modified approach. Both approaches showed no statistically significant differences between primary and secondary outcomes. The original approach yielded good to excellent results in all patients (21/21) at the last follow-up, with a mean MEPS score of 98.5 and a UCLA score of 34.7. The modified approach resulted in good to excellent functional outcomes in 22 of 24 patients, with a mean MEPS score of 95.8 and a UCLA score of 34.3. The mean arch elbow motion was 125.3° (11° less than the undamaged arm) in the original approach and 123.5° (13° less than the undamaged arm) in the modified approach.

CONCLUSION: MIAMDAH provides a reliable alternative to laborious open approaches or risky MIPO approaches described to date. The modified version offers a broader MIPO window, which enhances surgery comfort and may reduce the complication rate.

PMID:40517641 | DOI:10.1016/j.injury.2025.112515

Discharges to rehabilitation after bilateral lower extremity fractures - there is no racial disparity

Injury -

Injury. 2025 Jun 6;56(8):112506. doi: 10.1016/j.injury.2025.112506. Online ahead of print.

ABSTRACT

PURPOSE: Certain trauma populations require rehabilitation services after inpatient management. However, studies have shown implicit bias against African American patients regarding the access to rehabilitation services. The purpose of this study was to assess the variance in rehabilitation discharges of adult patients who sustained lower extremity bilateral long bone fractures comparing African American and Caucasian patients.

METHODS: The study included African American and Caucasian adult patients who sustained bilateral long bone fractures of the lower extremities. Data was extracted from the National Inpatient Sample (NIS) database of 2019. Demographic information, clinical characteristics, comorbidities, and outcomes for all qualifying patients were compared using propensity score matching analysis.

RESULTS: Propensity matching analysis created 361 pairs of patients. The two groups (Caucasian patients and African American patients) had comparable characteristics including age (median years [IQR], 42 [30 - 57] vs. 42 [29 - 58], P = 0.790), sex ([male] 60.7 % vs, 60.7 %), injury severity score (ISS) score (median [IQR], 14 [4 - 26] vs. 14 [5 - 29], P = 0.344) and insurance status (private, 125 (34.6 %) vs. 125 (34.6 %)). The analyses found no significant differences in rehabilitation disposition (199 (56.9 %) vs. 185 (53.8 %), P = 0.460, hospital length of stay (median days [95 % CI], 9 [8, 10] vs. 10 [9, 11], P = 0.116) and overall in-hospital mortality (11 (3.0 %) vs. 17 (4.7 %), P = 0.327) between the groups.

CONCLUSION: Our study identified no significant bias against African American patients who suffered from bilateral long bone fractures of the lower extremities and required rehabilitation services.

PMID:40517640 | DOI:10.1016/j.injury.2025.112506

Risk factors for recurrent lumbar disc herniation after unilateral biportal endoscopy: a retrospective study

International Orthopaedics -

Int Orthop. 2025 Jun 14. doi: 10.1007/s00264-025-06577-2. Online ahead of print.

ABSTRACT

PURPOSE: Unilateral biportal endoscopy (UBE) is a predominantly minimally invasive surgical technique for addressing LDH. Nonetheless, recurrent lumbar disc herniation (rLDH) remains the predominant reason for reoperation following UBE. This retrospective study examined the risk factors and reoperation rates for rLDH following UBE. This study aimed to examine the risk factors associated with rLDH and the reoperation rate after single-level UBE.

METHODS: We retrospectively analyzed 205 patients who underwent UBE for single-level LDH from 2019 to 2023 to determine reoperation causes and related risk variables. Reoperation was characterized as the postoperative radiological evidence of persistent symptomatic disc herniation at the same level, necessitating further surgical intervention. We gathered radiographic and demographic parameters preoperatively and postoperatively. Patients with recurrent LDH had additional evaluation during recurrence and revision operations.

RESULTS: Of the 205 patients, 21 (10.2%) required further rLDH revision surgery. The multivariate analysis indicated that obesity and elevated fasting blood glucose (FBG) levels were independent risk variables with strong predictive value for reoperation after controlling for other potential risk factors. Based on the receiver operating characteristic curve analysis, the cutoff points for UBE were body mass index (BMI) = 25.775 kg/m2 and FBG = 5.155 mmol/L.

CONCLUSION: This study identified obesity (BMI > 25.775 kg/m²) and elevated FBG levels (> 5.155 mmol/L) as independent risk factors for UBE reoperation. Hence, we recommend longer rehabilitation interventions, such as wearing a suitable brace and strengthening the paraspinal muscles, for patients with obesity and high FBG who undergo UBE.

PMID:40515760 | DOI:10.1007/s00264-025-06577-2

Three dimensional printing patient specific cutting guides for Pes cavus midfoot osteotomy-a retrospective cohort comparative study

International Orthopaedics -

Int Orthop. 2025 Jun 14. doi: 10.1007/s00264-025-06572-7. Online ahead of print.

ABSTRACT

OBJECTIVE: This comparative cohort study evaluates the clinical efficacy of 3D-printed patient-specific cutting guides (PSCGs) versus conventional manual techniques in correcting rigid midfoot pes cavus deformities.

METHODS: A retrospective analysis of 40 patients (80 feet) undergoing Cole osteotomy between 2021 and 2023 was conducted. Patients were stratified into two matched cohorts: Group A (manual osteotomy, n = 20) and Group B (PSCG-assisted, n = 20). Radiographic parameters (Meary's angle, TMI, TCA, Djian-Annonier angle, Pitch angle) and functional outcomes (VAS, AOFAS, SF-36) were analyzed preoperatively and at mean 17-month follow-up. Surgical metrics including operative time, fluoroscopy frequency, and complication rates were systematically compared.

RESULTS: Radiographic analysis demonstrated superior angular correction in the PSCG-assisted cohort versus conventional osteotomy, with significantly improved bilateral Meary's angle (Right: 1.94°±0.62 vs. 6.04°±2.20, P < 0.05; Left: 1.62°±0.54 vs. 6.39°±2.04, P < 0.05) and TMI angle (Right: 4.32°±3.14 vs. 8.51°±8.12, P < 0.05; Left: 4.74°±2.44 vs. 8.53°±5.93, P < 0.05). The PSCG technique achieved equivalent correction in TCA, Djian-Annonier, and Pitch angles while demonstrating enhanced consistency (38-66% reduction in standard deviations). Functionally, PSCG-assisted procedures yielded superior AOFAS scores (97.71 ± 0.77 vs. 92.07 ± 2.25, Δ = 5.64 [95%CI 4.54-6.74], P < 0.05) and SF-36 outcomes, particularly in general health (Δ = 16.96, P < 0.05) and mental well-being (Δ = 7.92, P = 0.001). Operative metrics favored PSCG with 36% shorter procedure time (82.9 ± 13.9 vs. 129.0 ± 39.6 min, P < 0.05) and 77% reduced intraoperative fluoroscopy (4.65 ± 1.06 vs. 20.07 ± 2.92 exposures, P < 0.05). No surgical site infections occurred in the PSCG group versus one superficial SSI in controls CONCLUSION: 3D-printed PSCGs provide anatomically precise, efficient correction of complex midfoot deformities while minimizing intraoperative radiation exposure, establishing this technology as a safe and reproducible alternative to conventional techniques.

PMID:40515759 | DOI:10.1007/s00264-025-06572-7

National 5-year data analysis of health outcomes in hospitalized geriatric patients with hip fracture

Injury -

Injury. 2025 Jun 6;56(8):112513. doi: 10.1016/j.injury.2025.112513. Online ahead of print.

ABSTRACT

BACKGROUND: Increasing awareness about fall prevention and osteoporosis screening could reduce the incidence of hip fractures in the elderly, and comprehensive care can improve outcomes. There is limited nationwide data on the health outcomes of hip fractures when comparing operative and non-operative approaches. The study objectives were to ascertain the short-term outcomes of older patients hospitalized with hip fractures and to elucidate the variables correlated with in-hospital mortality.

METHODS: This study utilized a retrospective dataset comprising hospitalized individuals aged ≥60 years who were admitted due to hip fractures during the fiscal years spanning from 2019 to 2023. The National Health Security Office conducted the diagnosis, employing the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, Thai Modification (ICD-10-TM) code S72. Surgical procedures pertinent to hip fractures were categorized under ICD-9-79.1, ICD-9-79.3, ICD-9-81.51, ICD-9-81.52, and ICD-9-81.53. Demographic information was analyzed through descriptive statistical methods. Factors associated with in-hospital mortality were assessed through both univariate and multivariate analyses.

RESULTS: Out of 115,333 diagnosed cases, the admission rate was 205.5 per 100,000 population, with 46.9 % undergoing surgery. The overall in-hospital mortality rate was 4.04 per 100,000 individuals. Patients who underwent surgery showed a lower in-hospital mortality rate compared to those who did not, recorded at 1.3 vs 1.9 (p < 0.05) for males and 2.1 vs 2.6 (p < 0.05) for females per 100,000 population. Outcomes at discharge for those receiving operative versus non-operative treatment revealed a mean length of stay (LOS) of 11.5 versus 10.8 days (p < 0.05), mean healthcare costs of $1973 versus $1554 (p < 0.05), and in-hospital mortality rates of 1.8 % versus 2.1 % (p < 0.05). Factors increasing mortality included age (70-80 years: OR 1.51, 95 %CI 1.30-1.74; ≥80 years: OR 2.59, 95 %CI 2.27-2.97), male gender: OR 1.69, 95 %CI 1.55-1.85, extracapsular fracture: OR 1.15, 95 %CI 1.05-1.25, and a LOS ≥10 days: OR 1.63, 95 %CI 1.49-1.78. Surgery associated with lower mortality: OR 0.88, 95 %CI 0.81-0.96.

CONCLUSION: Hip fracture patients who underwent surgery had better mortality outcomes than those who did not. Less than half of patients opted for surgery in the past five years. Therefore, it is essential to encourage surgical treatment for these patients.

PMID:40513174 | DOI:10.1016/j.injury.2025.112513

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